A Review on Application of Biosensors for Cancer Detection

Nilakshi Devi, Shakuntala Laskar

Abstract


Cancer is a deadly disease that has devastated many lives over the years. Cancer, when detected in the early stage, can be cured through proper treatment, increasing the life expectancy of the patient. Thus, it is very important to detect cancer at the early stage. The current method of cancer detection is biopsy which is a total invasive medical procedure. Owing to the several limitations of the time-consuming procedure of biopsy researchers and scientist all over the globe have turned their attention towards the development of instruments for rapid and non-invasive detection of cancer through detection of clinically recognized cancer biomarkers present in blood and other body fluid of cancer patients. This paper discusses some of the novel biomarkers used for cancer diagnosis along with the potential use of biosensors in early detection of cancer.

Keywords


Biomarkers, Biopsy, Biosensors, Cancer

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References


“Cancer: What you need to knowâ€, Medical News Today. [Online]. Available: https://www.medicalnewstoday.com/info/cancer-oncology (Accessed: Sept. 12, 2018).

“Cancer: What you need to knowâ€, Medical News Today. [Online]. Available: https://www.medicalnewstoday.com/info/cancer-oncology (Accessed: Sept. 12, 2018).

“Cancer: What you need to knowâ€, Medical News Today. [Online]. Available: https://www.medicalnewstoday.com/info/cancer-oncology (Accessed: Sept. 12, 2018).

N. L. Henry and D. F. Hayes, “Cancer Biomarkersâ€, Molecular Oncology, Vol. 6, 2012, pp. 140-146. Doi: https://doi.org/10.1016/j.molonc.2012.01.010

Hoseok, I. and J. Y. Cho, “Lung Cancer Biomarkers†in Advances in Clinical Chemistry, Gregory S. Makowski (ed.),Vol. 72, pp. 107-170, Elsevier, US, 2015. Doi: https://doi.org/10.1016/bs.acc.2015.07.003

L. H. Gam, “Breast Cancer and Protein Biomarkersâ€, World Journal of Experimental Medicine, Vol. 2, Issue No. 5, 2012, pp. 86-91. Doi: http://dx.doi.org/10.5493/wjem.v2.i5.86

G. Mor et al., “Serum Protein Markers for Early Detection of Ovarian Cancerâ€, Proceedings of the National Academy of Sciences, May 2005, Vol. 102, Issue No. 21, pp. 7677-7682. Doi: https://doi.org/10.1073/pnas.0502178102

M. Herreros-Villanueva and L. Bujanda, “Non-invasive Biomarkers in Pancreatic Cancer Diagnosis: what we versus what we haveâ€, Annals of Translation Medicine, Vol. 4, Issue No. 7, 2016. Retrieved from http://atm.amegroups.com/article/view/9796

J. Lou, L. Zhang, S. Lv, C. Zhang and S. Jiang, “Biomarkers for Hepatocellular Carcinomaâ€, Biomarkers in Cancer, Vol. 9, 2017, pp. 1-9. Doi: http://doi.org/10.1177/1179299X16684640

P. O. Gaudreau, J. Stagg, D. Soulières and F. Saad, “The Present and Future of Biomarkers in Prostate Cancer: Proteomics, Genomics, and Immunology Advancementsâ€, Biomarkers in Cancer, Vol. 8 (Suppl. 2), 2016, pp. 15-33. Doi: https://doi.org/10.4137/BIC.S31802

G. Lech, R. SÅ‚otwiÅ„ski, M. SÅ‚odkowski and I. W. KrasnodÄ™bski, “Colorectal Cancer Tumor Markers and Biomarkers: Recent Therapeutic Advancesâ€, World Journal of Gastroenterology, Vol. 22, Issue No. 5, 2016, pp. 1745-1755. Doi: http://dx.doi.org/10.3748/wjg.v22.i5.1745

N. J. Farber, C. J. Kim, P. K. Modi, J. D. Hon, E. T. Sadimin and E. A. Singer, “Renal cell carcinoma: the search for a reliable biomarkerâ€, Translational Cancer Research, Vol. 6, Issue 3, 2017, pp. 620–632. Doi: http://doi.org/10.21037/tcr.2017.05.19

S. Saxena, B. Sankhla, K. S. Sundaragiri and A. Bhargava, “A Review of Salivary Biomarker: A Tool for Early Oral Cancer Diagnosisâ€, Advanced Biomedical Research, Vol. 6, 2017, pp. 90. http://doi.org/10.4103/2277-9175.211801

A. El-Jawahri, D. Patel, M. Zhang, N. Mladkova and A. Chakravarti, “Biomarkers of Clinical Responsiveness in Brain Tumor Patients: Progress and Potentialâ€, Molecular Diagnosis & Therapy, Vol. 12, Issue No. 4, July 2008, pp. 199–208. Doi: https://doi.org/10.1007/BF03256285

J. Prada-Arismendy, J. C. Arroyave and S. Röthlisberger, “Molecular Biomarkers in Acute Myeloid Leukemiaâ€, Blood Reviews, Vol. 31, Issue 1, 2017, pp. 63-76. Doi: https://doi.org/10.1016/j.blre.2016.08.005

E. K. Yim and J. S. Park, “Biomarkers in Cervical Cancerâ€, Biomarker Insights, Vol. 1, 2006, pp. 215-225. Doi: https://doi.org/10.1177%2F117727190600100015

Z. Jin, W. Jiang and L. Wang, “Biomarkers for Gastric Cancer: Progression in Early Diagnosis and prognosisâ€, Oncology Letters, Vol. 9, Issue No. 4, 2015, pp. 1502-1508. Doi: https://doi.org/10.3892/ol.2015.2959

E. S. Greenberg, K. K. Chong, K. T. Huynh, R. Tanaka and D. S. B. Hoon, “Epigenetic Biomarkers in Skin Cancerâ€, Cancer Letters, Vol. 342, Issue No. 2, 2014, pp. 170-177. Doi: https://doi.org/10.1016/j.canlet.2012.01.020

S. Kumar, A. Mohan and R. Guleria, “Biomarkers in Cancer Screening, Research and Detection: present, past and future: A Reviewâ€, Biomarkers, Vol. 11, Issue No. 5, 2006, pp. 385-405. Doi: https://doi.org/10.1080/13547500600775011

R. Mayeux, “Biomarkers: Potential Uses and Limitationsâ€, NeuroRx, Vol. 1, Issue No. 2, 2004, pp. 182-188. Doi: https://doi.org/10.1602/neurorx.1.2.182

B. Bohunicky and S. A. Mousa “Biosensors: the new wave in cancer diagnosisâ€, Nanotechnology, Science and Applications, Vol. 4, 2011, pp. 1-10. Doi: https://doi.org/10.2147/NSA.S13465

“Leland Clarkâ€, Wikipedia. [Online]. Available: https://en.wikipedia.org/wiki/Leland_Clark (Accessed: 12 Sept. 2018).

V. Perumal and U. Hashim, “Advances in Biosensors: Principle, architecture and applicationsâ€, Journal of Applied Biomedicine, Vol. 12, Issue No. 1, 2014, pp. 1-15. Doi: https://doi.org/10.1016/j.jab.2013.02.001

I. E. Tothill, “Biosensors for cancer marker diagnosisâ€, Seminars in Cell and Developmental Biology, Vol. 20, Issue 1, Feb. 2009, pp. 55-62. Doi: https://doi.org/10.1016/j.semcdb.2009.01.015

I. E. Tothill, “Biosensors for cancer marker diagnosisâ€, Seminars in Cell and Developmental Biology, Vol. 20, Issue 1, Feb. 2009, pp. 55-62. Doi: https://doi.org/10.1016/j.semcdb.2009.01.015

S. A. Soper et al., “Point-of-care biosensor systems for cancer diagnostics/prognosticsâ€, Biosensors and Bioelectronics, Vol. 21, Issue No. 10, 2006, pp. 1932-1942. Doi: https://doi.org/10.1016/j.bios.2006.01.006

J. Wang, “Electrochemical Biosensors: towards point-of-care cancer diagnosticsâ€, Biosensors and Bioelectronics, Vol. 21, Issue 10, 2006, pp. 1887-1892. Doi: https://doi.org/10.1016/j.bios.2005.10.027

S. Chaitra, C. Veena, K. S. Rao and P. Sharan, “SPR based biosensors for detection of abnormal growth of tissuesâ€, 2017 International Conference on Nextgen Electronic Technologies: Silicon to Software (ICNETS2), Chennai, 2017, pp. 149-153. Doi: 10.1109/ICNETS2.2017.8067918

M. T. Islam and M. Ashab-Uddin, “Biosensors, the Emerging Tools in the Identification and Detection of Cancer Markersâ€, Journal of Gynecology and Women’s Health, Vol. 5, Issue No. 4, 2017. Doi: http://dx.doi.org/10.19080/JGWH.2017.05.555667

W. Tan et al., “Optical Protein sensors for detecting cancer markers in salivaâ€, Biosensors and Bioelectronics, Vol. 24, Issue No. 2, 2008, pp. 266-271. Doi: https://doi.org/10.1016/j.bios.2008.03.037

J. Yuan, R. Duan, H. Yang, X. Luo and M. Xi. “Detection of serum human epididymis secretory protein 4 in patients with ovarian cancer using a label-free biosensor based on localized surface plasmon resonanceâ€, International Journal of Nanomedicine, Vol. 7, 2012, pp. 2921-2928. Doi: https://doi.org/10.2147/IJN.S32641

T. Kumeria, M. D. Kurkuri, K. R. Diener, L. Parkinson and D. Losic, “Label-free reflectometric interference microchip biosensor based on nanoporous alumina for detection of circulating tumour cellâ€, Biosensors and Bioelectronics, Vol. 35, Issue No. 1, May 2012, pp. 167-173. doi: https://doi.org/10.1016/j.bios.2012.02.038

A. Malima et al., “Highly sensitive microscale in vivo sensor enabled by electrophoretic assembly of nanoparticles for multiple biomarker detection†Lab on A Chip, Vol. 12, Issue No. 22, 2012, pp. 4748-4754. Doi: http://dx.doi.org/10.1039/C2LC40580F

P. Damborský, J. Å vitel and J. Katrlík, “Optical Biosensorsâ€, Essays in Biochemistry, Vol. 60, Issue No. 1, 2016, pp. 91-100. Doi: https://doi.org/10.1042/EBC20150010


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